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TTBOOK: DNA and Discovery Jessica Queller tested positive for the breast cancer gene BRCA. Michael Crichton discusses the ethics of gene patenting. Sean Carroll describes advances in DNA research. James Watson cracked the code of DNA. Sarah Waliany and Caroline Lang are young students making discoveries in science. Jessica Queller tells Anne Strainchamps why she decided to have a double mastectomy after she tested positive for the breast cancer gene and her mother died of ovarian cancer. Her book is called "Pretty Is What Changes."

MD and best-selling novelist Michael Crichton talks with Jim Fleming about the ethical problems he envisions with permitting patents on human DNA. Chrichton's latest novel is "Next."

Sean Carroll is the author of "The Making of the Fittest: DNA and the Ultimate Forensic Record of Evolution." He tells Steve Paulson about new discoveries in evolutionary history, including the existence and purpose of fossil genes. Carroll is an evolutionary biologist at the Howard Hughes Medical Institute and at the University of Wisconsin.

James Watson is famous for cracking the code of DNA, along with Francis Crick, and infamous for picking fights with other scientists and making inflammatory statements. His latest book, "Avoid Boring People" contains advice for young scientists. Watson talked to Steve Paulson and you can judge for yourself whether he's mellowed any.

Anne Strainchamps talks with two teenagers who were finalists in the Siemens Competition in Math, Science and Technology. Sarah Waliany and Caroline Lang explain what their experiments were about and why they like science.