Increasing habitat loss, fragmentation and wildlife mortality due to roads is widespread and not a unique problem to Arizona, however, it is one of the most aggressive areas in North America where efforts to mitigate these impacts are ongoing. Arizona Game and Fish Department works closely with various partners to seek innovative solutions to address wildlife-vehicle collisions while maintaining habitat connectivity. Many of these data-driven decisions are derived through research projects, including pre- and post-construction monitoring of mitigation efforts. A few of these projects include Arizona State Route 260 and US Highway 93 where safe passages are constructed for wildlife crossing these roads. Aside from traditional wildlife crossings, Arizona Game and Fish Department has also spearheaded innovative projects to retrofit existing highways, including the SR 260 Elk Crosswalk project and the I-17 Elk Fencing Project. This presentation will provide insight into various innovative wildlife-highway projects throughout Arizona and associated research findings.